Preparation of 24(R)- and 24(S)-5β-cholestane-3α,7α,24-triols and 25(R)- and 25(S)-5β-cholestane-3α,7α,26-triols by a hydroboration procedure
نویسندگان
چکیده
منابع مشابه
(20R,24R,25S)-3α,7α,12α,27-Tetraacetoxy-24,26-epoxy-5β-cholestane
In the title anhydro-scymnol tetra-acetate, C(35)H(54)O(9), the fused chair conformation of the cyclo-hexane A/B ring junction is cis with a 5β-H configuration. The compound has a trimethyl-ene oxide ring at position 24,26 and four acetate groups at the 3α,7α,12α,27 positions.
متن کاملStability of Cholesterol; Cholesterol-5β,6β-Epoxide; Cholesta-3,5-Dien-7-One, and 5α-Cholestane in Solution During Short-Term Storage
Because cholesterol and its oxide products (COPs) are used as standards during analysis, their stability and autoxidation were assessed under typical storage conditions. Individual toluene solutions of cholesterol; cholesterol5β, 6β-epoxide; cholesta-3,5-dien-7-one; and 5α-cholestane were prepared and aliquots were stored at 23 ± 2°C, 4°C, and -20°C for 7 days. Samples were removed from storage...
متن کاملThe zwitterion (23′E)-(23R,25S)-23-[1-(oxidoiminio)ethyl]-5β-spirostan-3β-yl acetate
The title steroidal compound, C(31)H(49)NO(5), resulted from the selective oximation of (23R)-23-acetyl-sarsasapogenin acetate. One- and two-dimensional (1)H and (13)C NMR spectra, as well as IR data, are in agreement with the presence of a ketoxime group at C-23. However, recrystallization in slightly acidic media affords the title compound in the rare zwitterionic oxime form, as a consequence...
متن کامل6-Hydroxyimino-5α-cholestane
The title compound, C(27)H(47)NO, is a steroid derivative composed of a saturated carbon fused-ring framework with an alkyl side chain. Ring bond lengths have normal values with an average of 1.533 (2) Å, while the cholestane side chain shows an average bond length of 1.533 (2) Å. The three cyclohexane rings adopt chair conformations or close to chair conformations while the cyclopentane ring i...
متن کامل5β-Dihydroprogesterone and Human Preterm Labor
We previously investigated the progesterone metabolite 5β-dihydroprogesterone (5βDHP) in relation to human parturition at term, demonstrating that peripheral venous concentrations decrease in association with the onset of spontaneous labour. In this study our aim was to determine if 5βDHP concentrations were lower in women presenting in spontaneous preterm labour than in controls matched for ge...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1978
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)41557-3